Update: A few MacTips readers have noted that this might not be a good solution for spam mail. Reason being is that any reasonably intelligent spammer would fake their e-mail address. Instead, perhaps this would be better suited for unwanted mail (mailing lists, etc..), but not necessarily spam.
A good way to help combat spam is to use Mail.app’s bounce feature. This returns the spam to the sender as if they sent it to an incorrect address. To bounce junk mail, Control+Click the message and click bounce.
When this popup appears, click OK.
You’ve now returned the message to the spammer.
This isn’t the only solution you should be using to combat spam, but it will help.


Scott Gardner
Per Apple Support, "Returning unwanted email
To discourage someone from sending you email, you can reject, or "bounce" their message, as long as their return address is valid. When you bounce a message, it appears to the sender that your address is invalid. This is useful for rejecting mass mailings from companies whose mailing lists you've been added to after buying products from them.
If you use the bounce feature for unsolicited email ("spam"), the mail will come back to you as undeliverable, because the return address on spam is usually not valid." August 24th, 2005 at 4:48 pm
Jeremy Kemp
While it's a neat concept, bouncing mail isn't a good idea in practice, because it's a rare (and not so bright) spammer who includes their real return address in their mail. August 24th, 2005 at 6:47 pm
Brad
I'll fix the post accordingly. August 24th, 2005 at 6:54 pm
Concetta
The key here is to bounce an email BEFORE you select it or open it. You do this by opening up your Mail viewer window all the way: double-click the bar at the bottom of the viewer - this will close the preview window (if yours is open).
Now you can click on any mail message WITHOUT opening it (the "unread" blue dot remains in front of the message).
When you bounce the message THIS way (unopened), you get this message from Apple: "It will appear that the message was sent to an incorrect address. This might help reduce unwanted email, provided that the sender’s return address is correct." In other words, the message behaves as if it were never received by you. April 13th, 2008 at 10:40 pm
Les
Just delete your spam, please. July 20th, 2008 at 4:18 pm