An easy way to manipulate the clipboard from the command line is by using the pbcopy and pbpaste commands.
pbcopy will copy standard input to the clipboard–the following would be example usages:
echo “MacTips Rocks” | pbcopy (Copies “MacTips Rocks” to the clipboard)
pbcopy < file (Copies the contents of file to the clipboard)
ls -la | pbcopy (Copies [...]

Safari has a feature called “Private Browsing” (Safari -> Private Browsing) which keeps Safari from recording information about the websites you visit. Here’s the official description:
Using Safari’s new Private Browsing feature, no information about where you visit on the Web, personal information you enter or pages you visit are saved or cached. It’s as if [...]

You probably already knew that Command+Clicking a link in Safari would open the link in a new window/tab.
Did you also know that you can do the same thing with a form button? Try Command+Clicking a form’s submit button. Magically the form is submitted to a new window or tab.

A quick way to access various system preferences (sound, display, keyboard) is to hold the option key while pressing one of the function keys. This will bring up the system preferences dialog for the selected function key.
For example, holding option while pressing the “Volume Up” function key will launch the System Preferences for sound.
[Via Mac [...]

An easy way to select a file or folder while in Finder is to begin typing the file or folder name.
For example, in the following image you can see there are multiple Applications that begin with the letter “T” (TextEdit, TextWrangler and Transmit):

By typing “T”, Finder selects TextEdit, the first application that begins with a [...]

Update: A few MacTips readers have noted that this might not be a good solution for spam mail. Reason being is that any reasonably intelligent spammer would fake their e-mail address. Instead, perhaps this would be better suited for unwanted mail (mailing lists, etc..), but not necessarily spam.
A good way to help combat spam is [...]

Looking for a way to access the search field in Safari from the keyboard?
It’s as easy as pressing .

In Firefox, this is the equivalent of pressing Ctrl+K.

Not actually super zoom, but after trying it you’ll see what I mean.
To enable zoom mode, type . Type the same thing to get out of it.
To zoom in or out, type with a - (minus) or + (plus), respectively.

To turn on inverse mode, type .
This will invert all of the colors on your screen.
To get out of inverse mode, type the same thing again.
[Submitted by Lexi]

A quick way to answer a prompt that comes up is to press the first letter of the word on the button you would be clicking.
So for the following prompt, I would type C for Cancel and Y for Yes.

This doesn’t seem to work all of the time on all prompts. However, if the selected [...]